Hypersensitivity?

Anyone know about hypersensitivity in infants?  Zoey seems to have a hard time transitioning from sleeping to eating to sleeping again after some playing.  She seems to cry a lot more than Stella and often, when she starts up, if you don’t just put her in her swing or down in a quiet place at her first frown she seems to escalate with the crying.  Also, the more you do- rocking, talking to her, walking with her, etc. the more agitated she gets.  There have been many times with substantial crying for the better part of an hour if you don’t get her right at the perfect time before she gets going.  She seems to have a hard time shutting out things around her or at least dealing with things when she is tired and crying.  It could be just that she is an active child too.  Her arms and legs certainly go a mile a minute when she is playing and wide awake!  I have also heard a theory about these really active infants that are sensitive ending up being ADHD kids, but that again is just an idea.  Who knows?  Any thoughts?  Not sure if its bad enough to call the Dr. for thoughts just yet..